What are some established factors or variables that should be considered in the single blind randomized controlled trial of the effect of acupuncture as adjunctive therapy on homeostasis model assessment- insulin resistance and health-related quality of life (HRQoL) in patients with type 2 diabetes?

2. Discuss how HRQoL as secondary outcome of this trial could be happened? Discuss the possibilities of any potential relationship between the primary (HOMA-IR) and secondary (HRQoL) outcomes. Thank you

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