RPL11, SBCS, and DKC1
8. Based on what you have covered in this case, which organelle dysfunction is suspected of causing the childrens illnesses? Explain your reasoning for this selection. 9. Based on whether a gene is autosomal dominant, autosomal recessive, or X-linked, and given the parents genotypes, be able to determine what are the chances of a child inheriting a specific disease. 10. What happens if the p53 tumor suppressor fails to activate during organelle dysfunction? 11. What happens when the ribosomal 60S unit fails to bind with the 40S unit? 15. What is Jacks disease called? Dyskeratosis Congenita, X linked and Shwachman-Diamond Syndrome17. How does disrupted mitochondrial formation and dysfunction affect the cell cycle?
18. How does disrupted ribosome formation and dysfunction affect the cell cycle?
19. How does disrupted endoplasmic reticulum formation and dysfunction affect the cell cycle?
20. How does disrupted Golgi apparatus formation and dysfunction affect the cell cycle?
21. Why was it necessary to determine if there was a genetic basis for the childrens illnesses
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